Michael SheenLizzy CaplanBeau BridgesJaeden LieberherBenjamin KoldykeBetty Gilpin
Teddy SearsCaitlin FitzgeraldJulianne NicholsonAllison JanneyAnnaleigh AshfordNicholas D'AgostoEmily KinneyJosh Charles
The series chronicles the unusual lives, romance and pop culture trajectory of William Masters and Virginia Johnson. Their research touched off the sexual revolution and took them from a mid-western teaching hospital in St. Louis to the cover of Time magazine.
The story tells about two young scientists â€“ Dr. William Masters and Virginia Johnson, his assistant. The main characters are exploring the most interesting topic for a person, their sexuality and the processes that occur in the brain during arousal and the highest pleasure. Of course, this study more practical than theoretical, so William and Virginia first tested all practice on them, and then went on the rest. They have become a kind of guinea pigs. The book that is written by William became extraordinarily popular, which caused great interest to the two sexologists.
When William Masters and Virginia Johnson began their study into human sexuality they had no idea what a complex beast they would be uncovering nor what beasts lurked within their own psyches. The fourth season of 'Masters of Sex' begins in 1968. The sexual revolution is growing, feminism is making itself felt and youth have taken the staid 50's and turned them into the swinging 60's. The two researches have become national identities, appearing on the cover of Time magazine and haveing numerous appearances on television. Bill and Virginia expand their private practice, having left the world of academia which was having trouble understanding whether the research they were doing was a worthy subject for funding or simply an exercise in smut.